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Base-Resolution Methylome of Retinal Pigment Epithelial Cells Used in the First Trial of Human Induced Pluripotent Stem Cell-Based Autologous Transplantation

The first-in-human trial of induced pluripotent stem cell (iPSC)-based autologous transplantation was successfully performed on a female patient with age-related macular degeneration. Here we delineated the base-resolution methylome of the iPSC-derived retinal pigment epithelium (iRPE) used in this...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Araki, Hiromitsu, Miura, Fumihito, Watanabe, Akira, Morinaga, Chikako, Kitaoka, Fumiyo, Kitano, Yuko, Sakai, Noriko, Shibata, Yumiko, Terada, Motoki, Goto, So, Yamanaka, Shinya, Takahashi, Masayo, Ito, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829753/
https://ncbi.nlm.nih.gov/pubmed/31564644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.08.014
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