Changepoint detection in base-resolution methylome data reveals a robust signature of methylated domain landscape

BACKGROUND: Base-resolution methylome data generated by whole-genome bisulfite sequencing (WGBS) is often used to segment the genome into domains with distinct methylation levels. However, most segmentation methods include many parameters to be carefully tuned and/or fail to exploit the unsurpassed...

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Bibliografische gegevens
Gepubliceerd in:BMC Genomics
Hoofdauteurs: Yokoyama, Takao, Miura, Fumihito, Araki, Hiromitsu, Okamura, Kohji, Ito, Takashi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2015
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Methodology Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534107/
https://ncbi.nlm.nih.gov/pubmed/26265481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1809-5
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