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Changepoint detection in base-resolution methylome data reveals a robust signature of methylated domain landscape
BACKGROUND: Base-resolution methylome data generated by whole-genome bisulfite sequencing (WGBS) is often used to segment the genome into domains with distinct methylation levels. However, most segmentation methods include many parameters to be carefully tuned and/or fail to exploit the unsurpassed...
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| Publicado no: | BMC Genomics |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4534107/ https://ncbi.nlm.nih.gov/pubmed/26265481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1809-5 |
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