Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils

Neutrophils produce high levels of reactive oxygen species (ROS) by NADPH oxidase that are crucial for host defense but can lead to tissue injury when produced in excess. We previously described that proliferating cell nuclear antigen (PCNA), a nuclear scaffolding protein pivotal in DNA synthesis, c...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Exp Med
Main Authors: Ohayon, Delphine, De Chiara, Alessia, Dang, Pham My-Chan, Thieblemont, Nathalie, Chatfield, Simon, Marzaioli, Viviana, Burgener, Sabrina Sofia, Mocek, Julie, Candalh, Céline, Pintard, Coralie, Tacnet-Delorme, Pascale, Renault, Gilles, Lagoutte, Isabelle, Favier, Maryline, Walker, Francine, Hurtado-Nedelec, Margarita, Desplancq, Dominique, Weiss, Etienne, Benarafa, Charaf, Housset, Dominique, Marie, Jean-Claude, Frachet, Philippe, El-Benna, Jamel, Witko-Sarsat, Véronique
פורמט: Artigo
שפה:Inglês
יצא לאור: Rockefeller University Press 2019
נושאים:
Research Articles
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829599/
https://ncbi.nlm.nih.gov/pubmed/31492810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20180371
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