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Proteinase 3 Interferes With C1q-Mediated Clearance of Apoptotic Cells
Proteinase 3 (PR3) is the autoantigen in granulomatosis with polyangiitis, an autoimmune necrotizing vasculitis associated with anti-neutrophil cytoplasmic antibodies (ANCAs). Moreover, PR3 is a serine protease whose membrane expression can potentiate inflammatory diseases such as ANCA-associated va...
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| Veröffentlicht in: | Front Immunol |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5932363/ https://ncbi.nlm.nih.gov/pubmed/29755460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00818 |
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