Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils

Neutrophils produce high levels of reactive oxygen species (ROS) by NADPH oxidase that are crucial for host defense but can lead to tissue injury when produced in excess. We previously described that proliferating cell nuclear antigen (PCNA), a nuclear scaffolding protein pivotal in DNA synthesis, c...

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保存先:
書誌詳細
出版年:J Exp Med
主要な著者: Ohayon, Delphine, De Chiara, Alessia, Dang, Pham My-Chan, Thieblemont, Nathalie, Chatfield, Simon, Marzaioli, Viviana, Burgener, Sabrina Sofia, Mocek, Julie, Candalh, Céline, Pintard, Coralie, Tacnet-Delorme, Pascale, Renault, Gilles, Lagoutte, Isabelle, Favier, Maryline, Walker, Francine, Hurtado-Nedelec, Margarita, Desplancq, Dominique, Weiss, Etienne, Benarafa, Charaf, Housset, Dominique, Marie, Jean-Claude, Frachet, Philippe, El-Benna, Jamel, Witko-Sarsat, Véronique
フォーマット: Artigo
言語:Inglês
出版事項: Rockefeller University Press 2019
主題:
Research Articles
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829599/
https://ncbi.nlm.nih.gov/pubmed/31492810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20180371
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