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Functional Characterization of the Intact Diaphragm in a Nebulin-Based Nemaline Myopathy (NM) Model-Effects of the Fast Skeletal Muscle Troponin Activator tirasemtiv

Respiratory failure due to diaphragm dysfunction is considered a main cause of death in nemaline myopathy (NM) and we studied both isometric force and isotonic shortening of diaphragm muscle in a mouse model of nebulin-based NM (Neb cKO). A large contractile deficit was found in nebulin-deficient in...

詳細記述

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書誌詳細
出版年:Int J Mol Sci
主要な著者: Lee, Eun-Jeong, Kolb, Justin, Hwee, Darren T., Malik, Fady I., Granzier, Henk L.
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829460/
https://ncbi.nlm.nih.gov/pubmed/31658633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20205008
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