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Failure to identify modifiers of NEBULIN-related nemaline myopathy in two pre-clinical models of the disease

Nemaline myopathy is a rare neuromuscular disorder that affects 1 in 50,000 live births, with prevalence as high as 1 in 20,000 in certain populations. 13 genes have been linked to nemaline myopathy (NM), all of which are associated with the thin filament of the muscle sarcomere. Of the 13 associate...

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Bibliografiske detaljer
Udgivet i:Biol Open
Main Authors: Qiu, Boyang, Ruston, Julie, Granzier, Henk, Justice, Monica J., Dowling, James J.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6777365/
https://ncbi.nlm.nih.gov/pubmed/31530540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.044867
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