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Troponin activator augments muscle force in nemaline myopathy patients with nebulin mutations

BACKGROUND: Nemaline myopathy—the most common non-dystrophic congenital myopathy—is caused by mutations in thin filament genes, of which the nebulin gene is the most frequently affected one. The nebulin gene codes for the giant sarcomeric protein nebulin, which plays a crucial role in skeletal muscl...

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Detalhes bibliográficos
Main Authors: de Winter, Josine Marieke, Buck, Danielle, Hidalgo, Carlos, Jasper, Jeffrey R, Malik, Fady I, Clarke, Nigel F, Stienen, Ger J M, Lawlor, Michael W, Beggs, Alan H, Ottenheijm, Coen A C, Granzier, Henk
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865762/
https://ncbi.nlm.nih.gov/pubmed/23572184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmedgenet-2012-101470
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