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Genome-Wide Off-Target Analysis in CRISPR-Cas9 Modified Mice and Their Offspring
The emergence of the CRISPR-Cas9 system has triggered a technical revolution in mammalian genome editing. Compared to traditional gene-targeting strategies, CRISPR-Cas9 technology offers a more efficient and cost-effective approach for generating genetically modified animal models. However, off-targ...
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| Udgivet i: | G3 (Bethesda) |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Genetics Society of America
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6829146/ https://ncbi.nlm.nih.gov/pubmed/31492696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.119.400503 |
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