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Inducible Genome Editing with Conditional CRISPR/Cas9 Mice

Genetically engineered mouse models (GEMMs) are powerful tools by which to probe gene function in vivo, obtain insight into disease etiology, and identify modifiers of drug response. Increased sophistication of GEMMs has led to the design of tissue-specific and inducible models in which genes of int...

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Detalhes bibliográficos
Publicado no:G3 (Bethesda)
Main Authors: Katigbak, Alexandra, Robert, Francis, Paquet, Marilène, Pelletier, Jerry
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940154/
https://ncbi.nlm.nih.gov/pubmed/29519936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.117.300327
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