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Inducible Genome Editing with Conditional CRISPR/Cas9 Mice

Genetically engineered mouse models (GEMMs) are powerful tools by which to probe gene function in vivo, obtain insight into disease etiology, and identify modifiers of drug response. Increased sophistication of GEMMs has led to the design of tissue-specific and inducible models in which genes of int...

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Publicat a:G3 (Bethesda)
Autors principals: Katigbak, Alexandra, Robert, Francis, Paquet, Marilène, Pelletier, Jerry
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940154/
https://ncbi.nlm.nih.gov/pubmed/29519936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.117.300327
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