Tyrosyl-DNA Phosphodiesterase 1 and Topoisomerase I Activities as Predictive Indicators for Glioblastoma Susceptibility to Genotoxic Agents

Glioblastoma (GBM) patients have an estimated survival of ~15 months with treatment, and the standard of care only modestly enhances patient survival. Identifying biomarkers representing vulnerabilities may allow for the selection of efficacious chemotherapy options to address personalized variation...

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Publicat a:Cancers (Basel)
Autors principals: Wang, Wenjie, Rodriguez-Silva, Monica, Acanda de la Rocha, Arlet M., Wolf, Aizik L., Lai, Yanhao, Liu, Yuan, Reinhold, William C., Pommier, Yves, Chambers, Jeremy W., Tse-Dinh, Yuk-Ching
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6827102/
https://ncbi.nlm.nih.gov/pubmed/31547492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11101416
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