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Mammalian Tyrosyl-DNA Phosphodiesterases in the Context of Mitochondrial DNA Repair
Mammalian mitochondria contain four topoisomerases encoded in the nuclear genome: TOP1MT, TOP2α, TOP2β, and TOP3α. They also contain the two known tyrosyl-DNA phosphodiesterases (TDPs): TDP1 and TDP2, including a specific TDP2(S) isoform. Both TDP1 and TDP2 excise abortive topoisomerase cleavage com...
Tallennettuna:
| Julkaisussa: | Int J Mol Sci |
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| Päätekijät: | , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
MDPI
2019
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6628236/ https://ncbi.nlm.nih.gov/pubmed/31226795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20123015 |
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