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Mammalian Tyrosyl-DNA Phosphodiesterases in the Context of Mitochondrial DNA Repair
Mammalian mitochondria contain four topoisomerases encoded in the nuclear genome: TOP1MT, TOP2α, TOP2β, and TOP3α. They also contain the two known tyrosyl-DNA phosphodiesterases (TDPs): TDP1 and TDP2, including a specific TDP2(S) isoform. Both TDP1 and TDP2 excise abortive topoisomerase cleavage com...
שמור ב:
| הוצא לאור ב: | Int J Mol Sci |
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| Main Authors: | , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
MDPI
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6628236/ https://ncbi.nlm.nih.gov/pubmed/31226795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20123015 |
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