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Tyrosyl-DNA Phosdiesterase 1 (Tdp1) Inhibitors
Inhibitors of topoisomerase I (Top1) that result in stalled Top1 cleavage complexes (Top1cc) are commonly employed against cancer. Combination chemotherapy with DNA repair inhibitors can potentially improve response to these widely used chemotherapeutics. One line of inquiry focuses on inhibitors of...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3157054/ https://ncbi.nlm.nih.gov/pubmed/21843105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/13543776.2011.604314 |
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