Medroxyprogesterone acetate alters the vaginal microbiota and microenvironment in women and increases susceptibility to HIV-1 in humanized mice

The hormonal contraceptive medroxyprogesterone acetate (MPA) is associated with increased risk of human immunodeficiency virus (HIV), via incompletely understood mechanisms. Increased diversity in the vaginal microbiota modulates genital inflammation and is associated with increased HIV-1 acquisitio...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Wessels, Jocelyn M., Lajoie, Julie, Cooper, Maeve I. J. Hay, Omollo, Kenneth, Felker, Allison M., Vitali, Danielle, Dupont, Haley A., Nguyen, Philip V., Mueller, Kristen, Vahedi, Fatemeh, Kimani, Joshua, Oyugi, Julius, Cheruiyot, Juliana, Mungai, John N., Deshiere, Alexandre, Tremblay, Michel J., Mazzulli, Tony, Stearns, Jennifer C., Ashkar, Ali A., Fowke, Keith R., Surette, Michael G., Kaushic, Charu
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6826019/
https://ncbi.nlm.nih.gov/pubmed/31537512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.039669
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