Medroxyprogesterone acetate alters the vaginal microbiota and microenvironment in women and increases susceptibility to HIV-1 in humanized mice

The hormonal contraceptive medroxyprogesterone acetate (MPA) is associated with increased risk of human immunodeficiency virus (HIV), via incompletely understood mechanisms. Increased diversity in the vaginal microbiota modulates genital inflammation and is associated with increased HIV-1 acquisitio...

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Dettagli Bibliografici
Pubblicato in:Dis Model Mech
Autori principali: Wessels, Jocelyn M., Lajoie, Julie, Cooper, Maeve I. J. Hay, Omollo, Kenneth, Felker, Allison M., Vitali, Danielle, Dupont, Haley A., Nguyen, Philip V., Mueller, Kristen, Vahedi, Fatemeh, Kimani, Joshua, Oyugi, Julius, Cheruiyot, Juliana, Mungai, John N., Deshiere, Alexandre, Tremblay, Michel J., Mazzulli, Tony, Stearns, Jennifer C., Ashkar, Ali A., Fowke, Keith R., Surette, Michael G., Kaushic, Charu
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Ltd 2019
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6826019/
https://ncbi.nlm.nih.gov/pubmed/31537512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.039669
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