Differential Elevation of Inflammation and CD4(+) T Cell Activation in Kenyan Female Sex Workers and Non-Sex Workers Using Depot-Medroxyprogesterone Acetate

BACKGROUND: Depot Medroxyprogesterone (DMPA) is one of the most widely used contraceptives in Sub-Saharan Africa where HIV incidence is high. We explored the effect of DMPA on the activation of HIV cellular targets and inflammation as a possible mechanism of increased HIV risk with DMPA use. Since s...

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發表在:Front Immunol
Main Authors: Omollo, Kenneth, Lajoie, Julie, Oyugi, Julius, Wessels, Jocelyn M., Mwaengo, Dufton, Kimani, Joshua, Kaushic, Charu, Fowke, Keith R.
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2021
主題:
Immunology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7949914/
https://ncbi.nlm.nih.gov/pubmed/33717049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.598307
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