Medroxyprogesterone acetate alters the vaginal microbiota and microenvironment in women and increases susceptibility to HIV-1 in humanized mice

The hormonal contraceptive medroxyprogesterone acetate (MPA) is associated with increased risk of human immunodeficiency virus (HIV), via incompletely understood mechanisms. Increased diversity in the vaginal microbiota modulates genital inflammation and is associated with increased HIV-1 acquisitio...

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Dades bibliogràfiques
Publicat a:Dis Model Mech
Autors principals: Wessels, Jocelyn M., Lajoie, Julie, Cooper, Maeve I. J. Hay, Omollo, Kenneth, Felker, Allison M., Vitali, Danielle, Dupont, Haley A., Nguyen, Philip V., Mueller, Kristen, Vahedi, Fatemeh, Kimani, Joshua, Oyugi, Julius, Cheruiyot, Juliana, Mungai, John N., Deshiere, Alexandre, Tremblay, Michel J., Mazzulli, Tony, Stearns, Jennifer C., Ashkar, Ali A., Fowke, Keith R., Surette, Michael G., Kaushic, Charu
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Ltd 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6826019/
https://ncbi.nlm.nih.gov/pubmed/31537512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.039669
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