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Characterization of a KLK2-FGFR2 fusion gene in two cases of metastatic prostate cancer
BACKGROUND: The fibroblast growth factor receptor (FGFR) signaling pathway is activated in multiple tumor types through gene amplifications, single base substitutions, or gene fusions. Multiple small molecule kinase inhibitors targeting FGFR are currently being evaluated in clinical trials for patie...
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| Published in: | Prostate Cancer Prostatic Dis |
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| Main Authors: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6824932/ https://ncbi.nlm.nih.gov/pubmed/31043681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41391-019-0145-2 |
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