Characterization of a KLK2-FGFR2 fusion gene in two cases of metastatic prostate cancer

BACKGROUND: The fibroblast growth factor receptor (FGFR) signaling pathway is activated in multiple tumor types through gene amplifications, single base substitutions, or gene fusions. Multiple small molecule kinase inhibitors targeting FGFR are currently being evaluated in clinical trials for patie...

Full description

Saved in:
Bibliographic Details
Published in:Prostate Cancer Prostatic Dis
Main Authors: Krook, Melanie A., Barker, Hannah, Chen, Hui-Zi, Reeser, Julie W., Wing, Michele R., Martin, Dorrelyn, Smith, Amy M., Dao, Thuy, Bonneville, Russell, Samorodnitsky, Eric, Miya, Jharna, Freud, Aharon G., Monk, J. Paul, Clinton, Steven K., Roychowdhury, Sameek
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824932/
https://ncbi.nlm.nih.gov/pubmed/31043681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41391-019-0145-2
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items