Characterization of a KLK2-FGFR2 fusion gene in two cases of metastatic prostate cancer

BACKGROUND: The fibroblast growth factor receptor (FGFR) signaling pathway is activated in multiple tumor types through gene amplifications, single base substitutions, or gene fusions. Multiple small molecule kinase inhibitors targeting FGFR are currently being evaluated in clinical trials for patie...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Prostate Cancer Prostatic Dis
Egile Nagusiak: Krook, Melanie A., Barker, Hannah, Chen, Hui-Zi, Reeser, Julie W., Wing, Michele R., Martin, Dorrelyn, Smith, Amy M., Dao, Thuy, Bonneville, Russell, Samorodnitsky, Eric, Miya, Jharna, Freud, Aharon G., Monk, J. Paul, Clinton, Steven K., Roychowdhury, Sameek
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824932/
https://ncbi.nlm.nih.gov/pubmed/31043681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41391-019-0145-2
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