Tumor heterogeneity and acquired drug resistance in FGFR2-fusion-positive cholangiocarcinoma through rapid research autopsy

Cholangiocarcinoma is a highly aggressive and lethal malignancy, with limited treatment options available. Recently, FGFR inhibitors have been developed and utilized in FGFR-mutant cholangiocarcinoma; however, resistance often develops and the genomic determinants of resistance are not fully charact...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Cold Spring Harb Mol Case Stud
Main Authors: Krook, Melanie A., Bonneville, Russell, Chen, Hui-Zi, Reeser, Julie W., Wing, Michele R., Martin, Dorrelyn M., Smith, Amy M., Dao, Thuy, Samorodnitsky, Eric, Paruchuri, Anoosha, Miya, Jharna, Baker, Kaitlin R., Yu, Lianbo, Timmers, Cynthia, Dittmar, Kristin, Freud, Aharon G., Allenby, Patricia, Roychowdhury, Sameek
פורמט: Artigo
שפה:Inglês
יצא לאור: Cold Spring Harbor Laboratory Press 2019
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672025/
https://ncbi.nlm.nih.gov/pubmed/31371345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/mcs.a004002
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