Tumor heterogeneity and acquired drug resistance in FGFR2-fusion-positive cholangiocarcinoma through rapid research autopsy

Cholangiocarcinoma is a highly aggressive and lethal malignancy, with limited treatment options available. Recently, FGFR inhibitors have been developed and utilized in FGFR-mutant cholangiocarcinoma; however, resistance often develops and the genomic determinants of resistance are not fully charact...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Mol Case Stud
Main Authors: Krook, Melanie A., Bonneville, Russell, Chen, Hui-Zi, Reeser, Julie W., Wing, Michele R., Martin, Dorrelyn M., Smith, Amy M., Dao, Thuy, Samorodnitsky, Eric, Paruchuri, Anoosha, Miya, Jharna, Baker, Kaitlin R., Yu, Lianbo, Timmers, Cynthia, Dittmar, Kristin, Freud, Aharon G., Allenby, Patricia, Roychowdhury, Sameek
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672025/
https://ncbi.nlm.nih.gov/pubmed/31371345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/mcs.a004002
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