Tumor heterogeneity and acquired drug resistance in FGFR2-fusion-positive cholangiocarcinoma through rapid research autopsy

Cholangiocarcinoma is a highly aggressive and lethal malignancy, with limited treatment options available. Recently, FGFR inhibitors have been developed and utilized in FGFR-mutant cholangiocarcinoma; however, resistance often develops and the genomic determinants of resistance are not fully charact...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Cold Spring Harb Mol Case Stud
Κύριοι συγγραφείς: Krook, Melanie A., Bonneville, Russell, Chen, Hui-Zi, Reeser, Julie W., Wing, Michele R., Martin, Dorrelyn M., Smith, Amy M., Dao, Thuy, Samorodnitsky, Eric, Paruchuri, Anoosha, Miya, Jharna, Baker, Kaitlin R., Yu, Lianbo, Timmers, Cynthia, Dittmar, Kristin, Freud, Aharon G., Allenby, Patricia, Roychowdhury, Sameek
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Cold Spring Harbor Laboratory Press 2019
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672025/
https://ncbi.nlm.nih.gov/pubmed/31371345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/mcs.a004002
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