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A negative feedback regulatory loop between miR-138 and TP53 is mediated by USP10
TP53 is a critical tumor suppressor. In approximately 50% of human cancers the TP53 gene is either lost or mutated. The expression level of TP53 in the cells is tightly controlled by a fine-tune machinery, mainly through the Mdm2-mediated ubiquitination pathway. On the other side, the ubiquitinated...
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| Pubblicato in: | Oncotarget |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Impact Journals LLC
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6824876/ https://ncbi.nlm.nih.gov/pubmed/31695837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27275 |
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