Disruption of TP63-miR-27a* Feedback Loop by Mutant TP53 in Head and Neck Cancer

BACKGROUND: Alterations in the epidermal growth factor receptor and PI3K pathways in head and neck squamous cell carcinomas (HNSCCs) are frequent events that promote tumor progression. Ectopic expression of the epidermal growth factor receptor–targeting microRNA (miR), miR-27a* (miR-27a-5p), inhibit...

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Bibliographic Details
Published in:J Natl Cancer Inst
Main Authors: Chari, Nikhil S, Ivan, Cristina, Le, Xiandong, Li, Jinzhong, Mijiti, Ainiwaer, Patel, Ameeta A, Osman, Abdullah A, Peterson, Christine B, Williams, Michelle D, Pickering, Curtis R, Caulin, Carlos, Myers, Jeffrey N, Calin, George A, Lai, Stephen Y
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7073912/
https://ncbi.nlm.nih.gov/pubmed/31124563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djz097
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