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Disruption of TP63-miR-27a* Feedback Loop by Mutant TP53 in Head and Neck Cancer

BACKGROUND: Alterations in the epidermal growth factor receptor and PI3K pathways in head and neck squamous cell carcinomas (HNSCCs) are frequent events that promote tumor progression. Ectopic expression of the epidermal growth factor receptor–targeting microRNA (miR), miR-27a* (miR-27a-5p), inhibit...

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Détails bibliographiques
Publié dans:J Natl Cancer Inst
Auteurs principaux: Chari, Nikhil S, Ivan, Cristina, Le, Xiandong, Li, Jinzhong, Mijiti, Ainiwaer, Patel, Ameeta A, Osman, Abdullah A, Peterson, Christine B, Williams, Michelle D, Pickering, Curtis R, Caulin, Carlos, Myers, Jeffrey N, Calin, George A, Lai, Stephen Y
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7073912/
https://ncbi.nlm.nih.gov/pubmed/31124563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djz097
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