iASPP/p63 autoregulatory feedback loop is required for the homeostasis of stratified epithelia

iASPP, an inhibitory member of the ASPP (apoptosis stimulating protein of p53) family, is an evolutionarily conserved inhibitor of p53 which is frequently upregulated in human cancers. However, little is known about the role of iASPP under physiological conditions. Here, we report that iASPP is a cr...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Chikh, Anissa, Matin, Rubeta N H, Senatore, Valentina, Hufbauer, Martin, Lavery, Danielle, Raimondi, Claudio, Ostano, Paola, Mello-Grand, Maurizia, Ghimenti, Chiara, Bahta, Adiam, Khalaf, Sahira, Akgül, Baki, Braun, Kristin M, Chiorino, Giovanna, Philpott, Michael P, Harwood, Catherine A, Bergamaschi, Daniele
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2011
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199390/
https://ncbi.nlm.nih.gov/pubmed/21897369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.302
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars