FHL2 interacts with iASPP and impacts the biological functions of leukemia cells

iASPP is an inhibitory member of apoptosis-stimulating proteins of p53 (ASPP) family, which inhibits p53-dependent apoptosis. iASPP was highly expressed in acute leukemia, inhibited leukemia cells apoptosis and promoted leukemogenesis. In order to clarify its mechanism, a yeast two-hybrid screen was...

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Vydáno v:Oncotarget
Hlavní autoři: Lu, Wenting, Yu, Tengteng, Liu, Shuang, Li, Saisai, Li, Shouyun, Liu, Jia, Xu, Yingxi, Xing, Haiyan, Tian, Zheng, Tang, Kejing, Rao, Qing, Wang, Jianxiang, Wang, Min
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522200/
https://ncbi.nlm.nih.gov/pubmed/28402264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16617
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