Construction of a new anti-CD19 chimeric antigen receptor and the anti-leukemia function study of the transduced T cells

Chimeric antigen receptor (CAR) transduced T cells have been used to efficiently kill the target tumor cells depending on the single chain variable fragment (scFv) against the specific tumor associated antigen. Here we show the high specific cytotoxicity of the CAR-T cells with very low effector to...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: An, Na, Tao, Zhongfei, Li, Saisai, Xing, Haiyan, Tang, Kejing, Tian, Zheng, Rao, Qing, Wang, Min, Wang, Jianxiang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891147/
https://ncbi.nlm.nih.gov/pubmed/26840021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7079
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