Construction of a new anti-CD19 chimeric antigen receptor and the anti-leukemia function study of the transduced T cells

Chimeric antigen receptor (CAR) transduced T cells have been used to efficiently kill the target tumor cells depending on the single chain variable fragment (scFv) against the specific tumor associated antigen. Here we show the high specific cytotoxicity of the CAR-T cells with very low effector to...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: An, Na, Tao, Zhongfei, Li, Saisai, Xing, Haiyan, Tang, Kejing, Tian, Zheng, Rao, Qing, Wang, Min, Wang, Jianxiang
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891147/
https://ncbi.nlm.nih.gov/pubmed/26840021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7079
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