Overexpression of iASPP is required for autophagy in response to oxidative stress in choriocarcinoma

BACKGROUND: Gestational trophoblastic disease (GTD) is a heterogeneous group of diseases developed from trophoblasts. ASPP (Ankyrin-repeat, SH3-domain and proline-rich region containing protein) family proteins, ASPP1 and ASPP2, have been reported to be dysregulated in GTD. They modulate p53 activit...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Chan, Ka-Kui, Wong, Esther Shuk-Ying, Wong, Ivy Tsz-Lo, Cheung, Claire Ling-Yang, Wong, Oscar Gee-Wan, Ngan, Hextan Yuen-Sheung, Cheung, Annie Nga-Yin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6792270/
https://ncbi.nlm.nih.gov/pubmed/31615473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-6206-z
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