iASPP facilitates tumor growth by promoting mTOR-dependent autophagy in human non-small-cell lung cancer

Autophagy serves a critical function in the pathogenesis, response to therapy and clinical outcome in cancers. Although a recent report showed a role of iASPP in suppressing autophagy, its potential activity as a regulator of autophagy has not been investigated in lung cancer. Here we investigated t...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Xue, Yijun, Han, Haibo, Wu, Lina, Pan, Bo, Dong, Bin, Yin, C Cameron, Tian, Zhihua, Liu, Xijuan, Yang, Yue, Zhang, Hong, Chen, Yingyu, Chen, Jinfeng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5682680/
https://ncbi.nlm.nih.gov/pubmed/29072696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.515
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