MicroRNAs/TP53 feedback circuitry in glioblastoma multiforme

MicroRNAs (miRNAs) are increasingly implicated in regulating cancer initiation and progression. In this study, two miRNAs, miR-25 and -32, are identified as p53-repressed miRNAs by p53-dependent negative regulation of their transcriptional regulators, E2F1 and MYC. However, miR-25 and -32 result in...

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Autori principali: Suh, Sung-Suk, Yoo, Ji Young, Nuovo, Gerard J., Jeon, Young-Jun, Kim, Seokho, Lee, Tae Jin, Kim, Taewan, Bakàcs, Arianna, Alder, Hansjuerg, Kaur, Balveen, Aqeilan, Rami I., Pichiorri, Flavia, Croce, Carlo M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2012
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325690/
https://ncbi.nlm.nih.gov/pubmed/22431589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1202465109
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