Efficacy and Safety of Fixed-Dose Esketamine Nasal Spray Combined With a New Oral Antidepressant in Treatment-Resistant Depression: Results of a Randomized, Double-Blind, Active-Controlled Study (TRANSFORM-1)

BACKGROUND: About one-third of patients with depression fail to achieve remission despite treatment with multiple antidepressants and are considered to have treatment-resistant depression. METHODS: This Phase 3, double-blind, multicenter study enrolled adults with moderate-to-severe depression and n...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Int J Neuropsychopharmacol
Päätekijät: Fedgchin, Maggie, Trivedi, Madhukar, Daly, Ella J, Melkote, Rama, Lane, Rosanne, Lim, Pilar, Vitagliano, Dawn, Blier, Pierre, Fava, Maurizio, Liebowitz, Michael, Ravindran, Arun, Gaillard, Raphael, Ameele, Hans Van Den, Preskorn, Sheldon, Manji, Husseini, Hough, David, Drevets, Wayne C, Singh, Jaskaran B
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2019
Aiheet:
Regular Research Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6822141/
https://ncbi.nlm.nih.gov/pubmed/31290965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyz039
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