Effect of Esketamine Nasal Spray on Olfactory Function and Nasal Tolerability in Patients with Treatment-Resistant Depression: Results from Four Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase III Studies

BACKGROUND: Intranasal drug delivery offers a non-invasive and convenient dosing option for patients and physicians, especially for conditions requiring chronic/repeated-treatment administration. However, in some cases such delivery may be harmful to nasal and olfactory epithelia. OBJECTIVE: The aim...

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Detalhes bibliográficos
Publicado no:CNS Drugs
Main Authors: Doty, Richard L., Popova, Vanina, Wylie, Crystal, Fedgchin, Maggie, Daly, Ella, Janik, Adam, Ochs-Ross, Rachel, Lane, Rosanne, Lim, Pilar, Cooper, Kim, Melkote, Rama, Jamieson, Carol, Singh, Jaskaran, Drevets, Wayne C.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2021
Assuntos:
Original Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8310483/
https://ncbi.nlm.nih.gov/pubmed/34235612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40263-021-00826-9
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