Efficacy and Safety of Fixed-Dose Esketamine Nasal Spray Combined With a New Oral Antidepressant in Treatment-Resistant Depression: Results of a Randomized, Double-Blind, Active-Controlled Study (TRANSFORM-1)

BACKGROUND: About one-third of patients with depression fail to achieve remission despite treatment with multiple antidepressants and are considered to have treatment-resistant depression. METHODS: This Phase 3, double-blind, multicenter study enrolled adults with moderate-to-severe depression and n...

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Bibliografske podrobnosti
izdano v:Int J Neuropsychopharmacol
Main Authors: Fedgchin, Maggie, Trivedi, Madhukar, Daly, Ella J, Melkote, Rama, Lane, Rosanne, Lim, Pilar, Vitagliano, Dawn, Blier, Pierre, Fava, Maurizio, Liebowitz, Michael, Ravindran, Arun, Gaillard, Raphael, Ameele, Hans Van Den, Preskorn, Sheldon, Manji, Husseini, Hough, David, Drevets, Wayne C, Singh, Jaskaran B
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
Regular Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6822141/
https://ncbi.nlm.nih.gov/pubmed/31290965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyz039
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