NSUN2 introduces 5-methylcytosines in mammalian mitochondrial tRNAs

Expression of human mitochondrial DNA is indispensable for proper function of the oxidative phosphorylation machinery. The mitochondrial genome encodes 22 tRNAs, 2 rRNAs and 11 mRNAs and their post-transcriptional modification constitutes one of the key regulatory steps during mitochondrial gene exp...

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Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Van Haute, Lindsey, Lee, Song-Yi, McCann, Beverly J, Powell, Christopher A, Bansal, Dhiru, Vasiliauskaitė, Lina, Garone, Caterina, Shin, Sanghee, Kim, Jong-Seo, Frye, Michaela, Gleeson, Joseph G, Miska, Eric A, Rhee, Hyun-Woo, Minczuk, Michal
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2019
Onderwerpen:
RNA and RNA-protein complexes
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6822013/
https://ncbi.nlm.nih.gov/pubmed/31276587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz559
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