5-methylcytosine promotes mRNA export — NSUN2 as the methyltransferase and ALYREF as an m(5)C reader

5-methylcytosine (m(5)C) is a post-transcriptional RNA modification identified in both stable and highly abundant tRNAs and rRNAs, and in mRNAs. However, its regulatory role in mRNA metabolism is still largely unknown. Here, we reveal that m(5)C modification is enriched in CG-rich regions and in regi...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cell Res
Auteurs principaux: Yang, Xin, Yang, Ying, Sun, Bao-Fa, Chen, Yu-Sheng, Xu, Jia-Wei, Lai, Wei-Yi, Li, Ang, Wang, Xing, Bhattarai, Devi Prasad, Xiao, Wen, Sun, Hui-Ying, Zhu, Qin, Ma, Hai-Li, Adhikari, Samir, Sun, Min, Hao, Ya-Juan, Zhang, Bing, Huang, Chun-Min, Huang, Niu, Jiang, Gui-Bin, Zhao, Yong-Liang, Wang, Hai-Lin, Sun, Ying-Pu, Yang, Yun-Gui
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5594206/
https://ncbi.nlm.nih.gov/pubmed/28418038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2017.55
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