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5-methylcytosine mediates nuclear export of mRNA

5-methylcytosine was shown before to be an epitranscriptomic mark. Yang et al. now explored the unique topology of this mRNA modification, identified its writer and demonstrated its involvement in nuclear-cytoplasmic shuttling mediated by a specific reader.

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Detalhes bibliográficos
Publicado no:Cell Res
Main Authors: Dominissini, Dan, Rechavi, Gideon
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518879/
https://ncbi.nlm.nih.gov/pubmed/28534483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2017.73
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