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Archaeal NSUN6 catalyzes m(5)C72 modification on a wide-range of specific tRNAs

Human NOL1/NOP2/Sun RNA methyltransferase family member 6 (hNSun6) generates 5-methylcytosine (m(5)C) at C72 of four specific tRNAs, and its homologs are present only in higher eukaryotes and hyperthermophilic archaea. Archaeal NSun6 homologs possess conserved catalytic residues, but have distinct d...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Li, Jing, Li, Hao, Long, Tao, Dong, Han, Wang, En-Duo, Liu, Ru-Juan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6393295/
https://ncbi.nlm.nih.gov/pubmed/30541086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1236
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