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Archaeal NSUN6 catalyzes m(5)C72 modification on a wide-range of specific tRNAs

Human NOL1/NOP2/Sun RNA methyltransferase family member 6 (hNSun6) generates 5-methylcytosine (m(5)C) at C72 of four specific tRNAs, and its homologs are present only in higher eukaryotes and hyperthermophilic archaea. Archaeal NSun6 homologs possess conserved catalytic residues, but have distinct d...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Li, Jing, Li, Hao, Long, Tao, Dong, Han, Wang, En-Duo, Liu, Ru-Juan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6393295/
https://ncbi.nlm.nih.gov/pubmed/30541086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1236
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