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Archaeal NSUN6 catalyzes m(5)C72 modification on a wide-range of specific tRNAs

Human NOL1/NOP2/Sun RNA methyltransferase family member 6 (hNSun6) generates 5-methylcytosine (m(5)C) at C72 of four specific tRNAs, and its homologs are present only in higher eukaryotes and hyperthermophilic archaea. Archaeal NSun6 homologs possess conserved catalytic residues, but have distinct d...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Li, Jing, Li, Hao, Long, Tao, Dong, Han, Wang, En-Duo, Liu, Ru-Juan
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6393295/
https://ncbi.nlm.nih.gov/pubmed/30541086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1236
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