Polyadenylation and degradation of structurally abnormal mitochondrial tRNAs in human cells

RNA 3′ polyadenylation is known to serve diverse purposes in biology, in particular, regulating mRNA stability and translation. Here we determined that, upon exposure to high levels of the intercalating agent ethidium bromide (EtBr), greater than those required to suppress mitochondrial transcriptio...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Toompuu, Marina, Tuomela, Tea, Laine, Pia, Paulin, Lars, Dufour, Eric, Jacobs, Howard T
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
RNA and RNA-protein complexes
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6007314/
https://ncbi.nlm.nih.gov/pubmed/29518244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky159
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