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Alternative polyadenylation confers Pten mRNAs stability and resistance to microRNAs
Fine regulation of the phosphatase and tensin homologue (PTEN) phosphatase dosage is critical for homeostasis and tumour suppression. The 3′-untranslated region (3′-UTR) of Pten mRNA was extensively linked to post-transcriptional regulation by microRNAs (miRNAs). In spite of this critical regulatory...
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| 出版年: | Nucleic Acids Res |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6212768/ https://ncbi.nlm.nih.gov/pubmed/30053103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky666 |
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