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On the availability of microRNA-induced silencing complexes, saturation of microRNA-binding sites and stoichiometry

Several authors have suggested or inferred that modest changes in microRNA expression can potentiate or impinge on their capacity to mediate gene repression, and that doing so could play a significant role in diseases. Such interpretations are based on several assumptions, namely: (i) changes in mic...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Mayya, Vinay K., Duchaine, Thomas F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2015
Onderwerpen:
RNA
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551941/
https://ncbi.nlm.nih.gov/pubmed/26227970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv720
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