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On the availability of microRNA-induced silencing complexes, saturation of microRNA-binding sites and stoichiometry

Several authors have suggested or inferred that modest changes in microRNA expression can potentiate or impinge on their capacity to mediate gene repression, and that doing so could play a significant role in diseases. Such interpretations are based on several assumptions, namely: (i) changes in mic...

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Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: Mayya, Vinay K., Duchaine, Thomas F.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
Teme:
RNA
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551941/
https://ncbi.nlm.nih.gov/pubmed/26227970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv720
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