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Alternative Polyadenylation of mRNAs: 3′-Untranslated Region Matters in Gene Expression

Almost all of eukaryotic mRNAs are subjected to polyadenylation during mRNA processing. Recent discoveries showed that many of these mRNAs contain more than one polyadenylation sites in their 3′ untranslated regions (UTR) and that alternative polyadenylation (APA) is prevalent among these genes. Man...

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Bibliographic Details
Published in:Mol Cells
Main Authors: Yeh, Hsin-Sung, Yong, Jeongsik
Format: Artigo
Language:Inglês
Published: Korean Society for Molecular and Cellular Biology 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4844933/
https://ncbi.nlm.nih.gov/pubmed/26912084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2016.0035
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