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Progressive lengthening of 3′ untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development

The 3′ untranslated regions (3′ UTRs) of mRNAs contain cis-acting elements for posttranscriptional regulation of gene expression. Here, we report that mouse genes tend to express mRNAs with longer 3′ UTRs as embryonic development progresses. This global regulation is controlled by alternative polyad...

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Detalhes bibliográficos
Main Authors: Ji, Zhe, Lee, Ju Youn, Pan, Zhenhua, Jiang, Bingjun, Tian, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669788/
https://ncbi.nlm.nih.gov/pubmed/19372383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900028106
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