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Progressive lengthening of 3′ untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development

The 3′ untranslated regions (3′ UTRs) of mRNAs contain cis-acting elements for posttranscriptional regulation of gene expression. Here, we report that mouse genes tend to express mRNAs with longer 3′ UTRs as embryonic development progresses. This global regulation is controlled by alternative polyad...

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Bibliografske podrobnosti
Main Authors: Ji, Zhe, Lee, Ju Youn, Pan, Zhenhua, Jiang, Bingjun, Tian, Bin
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669788/
https://ncbi.nlm.nih.gov/pubmed/19372383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900028106
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