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Widespread mRNA polyadenylation events in introns indicate dynamic interplay between polyadenylation and splicing

mRNA polyadenylation and pre-mRNA splicing are two essential steps for the maturation of most human mRNAs. Studies have shown that some genes generate mRNA variants involving both alternative polyadenylation and alternative splicing. Polyadenylation in introns can lead to conversion of an internal e...

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Détails bibliographiques
Auteurs principaux: Tian, Bin, Pan, Zhenhua, Lee, Ju Youn
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1781347/
https://ncbi.nlm.nih.gov/pubmed/17210931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.5532707
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