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Nascent-seq indicates widespread cotranscriptional pre-mRNA splicing in Drosophila

To determine the prevalence of cotranscriptional splicing in Drosophila, we sequenced nascent RNA transcripts from Drosophila S2 cells as well as from Drosophila heads. Eighty-seven percent of the introns assayed manifest >50% cotranscriptional splicing. The remaining 13% are cotranscriptionally...

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Detalhes bibliográficos
Main Authors: Khodor, Yevgenia L., Rodriguez, Joseph, Abruzzi, Katharine C., Tang, Chih-Hang Anthony, Marr, Michael T., Rosbash, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243060/
https://ncbi.nlm.nih.gov/pubmed/22156210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.178962.111
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