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NASCENT-SEQ INDICATES WIDESPREAD COTRANSCRIPTIONAL RNA EDITING IN DROSOPHILA
The RNA editing enzyme ADAR chemically modifies adenosine (A) to inosine (I), which is interpreted by the ribosome as a guanosine. Here we assess cotranscriptional A-to-I editing in Drosophila, by isolating nascent RNA from adult fly heads and subjecting samples to high throughput sequencing. There...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3409466/ https://ncbi.nlm.nih.gov/pubmed/22658416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.05.002 |
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