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Alternative polyadenylation and differential expression of Shank mRNAs in the synaptic neuropil
The stability and dynamics of synapses rely on tight regulation of the synaptic proteome. Shank proteins, encoded by the three genes Shank1, Shank2 and Shank3 are scaffold molecules in the postsynaptic density of excitatory neurons that contribute to activity-dependent neuronal signalling. Mutations...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Royal Society
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3843870/ https://ncbi.nlm.nih.gov/pubmed/24298140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2013.0137 |
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