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Alternative polyadenylation and differential expression of Shank mRNAs in the synaptic neuropil

The stability and dynamics of synapses rely on tight regulation of the synaptic proteome. Shank proteins, encoded by the three genes Shank1, Shank2 and Shank3 are scaffold molecules in the postsynaptic density of excitatory neurons that contribute to activity-dependent neuronal signalling. Mutations...

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Detalhes bibliográficos
Main Authors: Epstein, Irina, Tushev, Georgi, Will, Tristan J., Vlatkovic, Irena, Cajigas, Iván J., Schuman, Erin M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843870/
https://ncbi.nlm.nih.gov/pubmed/24298140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2013.0137
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