Mammalian NSUN2 introduces 5-methylcytidines into mitochondrial tRNAs

Post-transcriptional modifications in mitochondrial tRNAs (mt-tRNAs) play critical roles in mitochondrial protein synthesis, which produces respiratory chain complexes. In this study, we took advantage of mass spectrometric analysis to map 5-methylcytidine (m(5)C) at positions 48–50 in eight mouse a...

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Foilsithe in:Nucleic Acids Res
Main Authors: Shinoda, Saori, Kitagawa, Sho, Nakagawa, Shinichi, Wei, Fan-Yan, Tomizawa, Kazuhito, Araki, Kimi, Araki, Masatake, Suzuki, Takeo, Suzuki, Tsutomu
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2019
Ábhair:
RNA and RNA-protein complexes
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895283/
https://ncbi.nlm.nih.gov/pubmed/31287866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz575
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