Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver Injury

Reversible infantile liver failure (RILF) is a unique heritable liver disease characterized by acute liver failure followed by spontaneous recovery at an early stage of life. Genetic mutations in MTU1 have been identified in RILF patients. MTU1 is a mitochondrial enzyme that catalyzes the 2-thiolati...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:PLoS Genet
Main Authors: Wu, Yong, Wei, Fan-Yan, Kawarada, Layla, Suzuki, Takeo, Araki, Kimi, Komohara, Yoshihiro, Fujimura, Atsushi, Kaitsuka, Taku, Takeya, Motohiro, Oike, Yuichi, Suzuki, Tsutomu, Tomizawa, Kazuhito
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045200/
https://ncbi.nlm.nih.gov/pubmed/27689697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006355
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker